Anais do X SIBGRAPI (1997) #AND16

Estudo da Morfologia Nuclear Miocárdica através de Técnicas de Quantificação Tridimensional e Microscopia Confocal com Varredura a Laser

Abstract. We propose a method to study myocardial fiber nuclei morphology through Laser Scanning Confocal Microscopy and multivariate statistical analysis. Image datasets are preprocessed by the means of a blind deconvolution algorithm and the nuclei are segmented by a simple mathematical morphology technique. Features are extracted in order to describe three-dimensional nuclear morphology. A multivariate statistical analysis is performed to discriminate different pathological nuclei and to clarify the idiopathic cardiomyopathy diseases.