Anais do X SIBGRAPI (1997) #AND16


Estudo da Morfologia Nuclear Miocárdica através de Técnicas de Quantificação Tridimensional e Microscopia Confocal com Varredura a Laser

Luiz Cláudio Parzianello, SP&D, Divisão de Informática, InCor/HCFMUSP
Maria de Lourdes Higuchi, Serviço de Anatomia Patológica, InCor/HCFMUSP
Sérgio Shiguemi Furuie, SP&D, Divisão de Informática, InCor/HCFMUSP

Abstract. We propose a method to study myocardial fiber nuclei morphology through Laser Scanning Confocal Microscopy and multivariate statistical analysis. Image datasets are preprocessed by the means of a blind deconvolution algorithm and the nuclei are segmented by a simple mathematical morphology technique. Features are extracted in order to describe three-dimensional nuclear morphology. A multivariate statistical analysis is performed to discriminate different pathological nuclei and to clarify the idiopathic cardiomyopathy diseases.

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